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Putting the Best Botox in Denver to the Test: The 5 Clinics That Made Our Cut

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We extensively test and research all services we review. Here's why you can trust us.

Injector Credentials: We looked for clinics staffed by Registered Nurses, Nurse Practitioners, or Physician Assistants with specialized training to ensure safety.

Consultation Quality: We prioritized places that offer thorough, educational assessments rather than rushing you straight to the chair.

Pricing Transparency: We selected businesses that are upfront about their unit costs and don't hide fees behind vague "per area" pricing.

Natural Aesthetic: We focused on clinics with a proven track record of "conservative" results that maintain facial expression.

Client Comfort: We considered the overall vibe and service level, ensuring the environment feels welcoming rather than clinical or intimidating.

Facing the mirror and noticing those first few lines sticking around longer than they used to can be a little daunting. We all want to look refreshed, like we just came back from a month-long vacation, without looking “frozen” or surprised. 

Finding the right injector is less about the product and entirely about the hands holding the needle. Residents of the Mile High City looking to smooth things out while keeping a natural expression need a provider who values subtlety over volume. 

I’ve rounded up the top Botox spots  in town that master the art of “you, but better.”

How much does Botox cost in Denver?

If you are budgeting for your first treatment, you should know that pricing in Denver is generally structured by the “unit” rather than by the area. Most reputable clinics in the city charge between $10 and $18 for every unit of Botox or Dysport used.

For a standard treatment, such as smoothing out a furrowed brow or softening crow’s feet, you are likely looking at a total bill ranging from $200 to $600 per visit. It depends on how strong your facial muscles are and how much movement you want to retain.

Think of it like buying high-quality fuel. You pay for exactly what you need to get the engine running smoothly, no more and no less.

1. The Luxe Room

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Website: https://www.luxeroomcosmetic.com/

Address: 3900 E Mexico Ave #100

Contact: +1 303-222-9546

Schedule: 

  • Mon – Wed & Fri: 9 AM – 5 PM
  • Thu: 9 AM – 7 PM
  • Sat: 9 AM – 1 PM

The Luxe Room has carved out a serious reputation in Denver for one main reason: their obsession with natural-looking results. Patients terrified of leaving a med spa looking like a different person will find a safe haven here. 

Led by Danielle Mathers, the founder and lead clinical leader behind The Luxe Room, uses proprietary techniques specifically designed to avoid that “overfilled” look. 

I appreciate that they charge per unit rather than per area, which feels much more honest and beneficial for your wallet.

Their strict no-tip policy removes that awkward moment at checkout and reinforces that you are paying for medical expertise, not just a service. 

While they have an exclusive skincare line called “EDIT,” the real draw here is the trust you can place in their RN and NP injectors. 

Keep in mind that if you want a full skin overhaul later, you’ll need to book a separate consultation from your injectable appointment.

Pros

  • Uses proprietary techniques for natural results
  • Strict no-tip policy keeps costs clear
  • Transparent per-unit pricing structure
  • Validated free parking at the Denver location

Cons

  • Requires a separate consultation for skin services

Highly recommend Ava for a top-tier experience

Ava G was AMAZING! She’s not only incredibly personable, but also extremely talented and thorough. She took the time to truly listen to my goals, offered thoughtful and unbiased recommendations, and educated me on realistic expectations throughout the process. I never felt pressured and felt completely at ease every step of the way – and I am obsessed with my results. Highly recommend Ava for a top-tier experience. The front desk team was also so warm and welcoming!

– Georgia Haley, Google Review

The level of skill and compassion at The Luxe Room is outstanding

The Luxe Room is truly exceptional. Brittany has been incredibly kind, patient, and helpful every step of the way, and Danielle has gone above and beyond for me—even staying after hours to dissolve my filler when I needed urgent help. Their professionalism, knowledge, and genuine care are unmatched. I felt completely safe, supported, and well-informed throughout the entire process. The level of skill and compassion at The Luxe Room is outstanding, and I couldn’t recommend their team more highly.

– Piera Marie, Google Review

2. Cheeky Denver

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Website: https://cheekydenver.com/

Address: 1525 N Raleigh St #300

Contact: +1 720-515-0720

Schedule: Mon – Fri: 10:30 AM – 5 PM

Cheeky Denver operates with a “less is more” philosophy, a refreshing change in an industry often criticized for excess. 

They specialize in facial balancing, meaning they look at your whole face to create harmony rather than just freezing a single wrinkle. 

This holistic view is backed by a solid medical foundation, as the clinic was founded by a board-certified Physician Assistant with emergency medicine experience. 

When I went in for my consultation, the provider spent nearly an hour just mapping my face and explaining the science before touching a needle, which instantly calmed my nerves about looking “done.” 

However, this isn’t the place for a lunch-break quick fix because they are very clear that they don’t do “rush jobs.” Nevertheless, if you want a luxury experience that feels like a concierge service, this is it.

Pros

  • “Less is More” philosophy prevents overdone looks
  • Lengthy 1-3 hour appointments for new patients
  • Founded by a board-certified Physician Assistant
  • Focuses on full facial balancing harmony

Cons

  • Not suitable for “quick fix” appointments

I had a wonderful experience

I had a wonderful experience with Elena and Allison at Cheeky Denver. Being a new patient and very nervous, Elena and Allison made me feel calm and comfortable. They explained every step from start to finish. Allison was extremely detail oriented and very knowledgeable when it came to Botox, Fillers and overall skin care. I’ve been so pleased with their professionalism and approach on listening to all my questions and concerns throughout the whole process. If you are looking for a Med Spa that you can trust and walk away with amazing results, Cheeky Denver is the spot for you.

– Lindsey Miller, Google Review

Was super happy with my results

I loved how easy their initial process was, and chatting with their staff, I didn’t feel like I was being upsold. I felt like I was being heard with my concerns and was able to have an easy/honest conversation about the aesthetic goals I have. The spot has easy parking, it’s super clean and just an overall great experience. Was super happy with my results and excited to have a place to rely on for Botox and fillers!

– Sarah Crow, Google Review

3. PREVA Aesthetics

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Website: https://prevaaesthetics.com/

Address: 4045 N Pecos St UNIT 100

Contact: +1 720-415-3992

Schedule: 

  • Mon – Wed: 8 AM – 6 PM
  • Thu: 8 AM – 5 PM
  • Fri & Sat: 8 AM – 4 PM

PREVA Aesthetics stands out because it is owned and operated by a Nurse Practitioner, giving it a distinctively clinical yet holistic edge. They examine your lifestyle alongside your skin, incorporating advice on vitamins and internal health into your aesthetic plan. 

The founder, Michelle Paty, has developed a signature technique that all their injectors use, ensuring you get consistent quality regardless of who you see. I love their focus on “preventative aesthetics,” which appeals to younger clients wanting to stop lines before they start deep setting. 

They also offer virtual consultations, which is a huge time-saver if you have a busy schedule. 

The main drawback is their limited footprint since they only have locations in Denver and Encinitas, California, so moving elsewhere means losing access. 

But if you are local, the highly trained staff of RNs and NPs offers a natural result guarantee that is hard to beat.

Pros

  • Owned and operated by a Nurse Practitioner
  • Focuses on preventative and holistic health
  • Signature technique used by all injectors
  • Virtual consultations available for convenience

Cons

  • Their only locations are Denver and Encinitas

I can’t say enough amazing things about Torri at Preva

I can’t say enough amazing things about Torri at Preva. I go to both the Denver and Encinitas locations, and am so lucky to be able to see my injector in two locations that I spend time in. I will drive over an hour to see her (even when there are a bunch of other injectors in my area I could see), because I absolutely trust that she has my best interest in mind and I am always super happy with my results. (Not to mention she is the nicest person with such a good heart). 10/10 would recommend.

– Meagan Taylor, Google Review

Great staff and beautiful new office

I’ve seen Michelle since she opened the Encinitas med spa and I won’t go anywhere else. I trust her implicitly and she always recommends the best treatment paths. Never an upsell, always kind and understanding. Great staff and beautiful new office. Highly recommend!

– Daphne Hagan, Google Review

4. Cherry Medical

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Website: https://cherrymedispa.com/

Address: 2200 W 29th Ave #102

Contact: +1 720-479-8793

Schedule: 

  • Mon – Fri: 10 AM – 6 PM
  • Sat: 9 AM – 4 PM

Located in the heart of LoHi, Cherry Medical positions itself as “affordable luxury,” offering high-end treatments without the exorbitant price tag you might find in other upscale neighborhoods. 

Their unique approach combines spa treatments, products, and home care, ensuring you aren’t just relying on injections alone.

The staff credentials here are impressive, featuring Board Certified Nurse Practitioners and Master Injectors. 

I also found their monthly specials to be a great way to try luxurious treatments without breaking the bank. Financing options like “Alle” and “Cherry Payment Plans” are available directly. 

The only catch is their schedule, since they are closed on Sundays and operate with shorter hours on Saturdays. 

This means weekend appointments are limited and can be highly competitive, especially for new patients trying to book a convenient time.

Pros

  • “Affordable Luxury” pricing model
  • Comprehensive “Three-Dimensional” care approach
  • Highly credentialed Master Injectors
  • Prime location in LoHi neighborhood

Cons

  • Closed on Sundays

The staff here is amazing and the whole office is great

Cannot recommend Ariana more. She’s so welcoming, knowledgeable, has such a talent for easing nerves, and does such a great job every time. Will make expert suggestions if I ask but never tries to pressure getting more things done or make you feel bad about yourself (quite the opposite!). Went to her (extremely nervous) for my first ever Botox years ago and will never go to anyone else, I recommend her to everyone. Also the rest of the staff here is amazing and the whole office is great. 100/10

– Katherine, Google Review

I am obsessed with the results of my Botox

I have been seeing Lauren P for a little over a year and I am obsessed with the results of my Botox and mini lip filler service. She is a great service provider and an RN. She understood the assignment 💕

– Erin Glassey, Google Review

5. GATTONI Medical Aesthetics

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Website: https://gattonimed.com/

Address: 250 Steele St Suite 214

Contact: +1 720-923-2200

Schedule: Mon – Sun: 8 AM – 8 PM

GATTONI Medical Aesthetics brings a warm Italian family vibe to the medical spa experience. 

Founded by Lea Gattoni, a Doctor of Medical Science, the clinic treats you like a long-term relationship rather than a transaction. 

This is one of the few places where you can get expert care on a Sunday, which is a lifesaver for anyone with a standard 9-to-5 job. Their holistic focus extends to wellness services like weight loss and women’s health, making it a comprehensive destination. 

I was impressed by the depth of experience here because some practitioners have nearly two decades in the field. They also act as a training facility for others, which speaks volumes about their safety standards. 

Note that they operate strictly by appointment, so you can’t just walk in off the street hoping for a quick touch-up.

Pros

  • Open 7 days a week including Sundays
  • Founder is a National Aesthetics Trainer
  • “Italian Family” atmosphere builds relationships
  • Extensive practitioner experience (19+ years)

Cons

  • Strictly by appointment only (no walk-ins)

I had the best experience getting my chin filler and Botox done

I had the best experience getting my chin filler and Botox done with Abby! She was incredibly sweet, compassionate, and made me feel so comfortable the entire time. She wasn’t pushy with treatments at all and genuinely listened to what I wanted instead of trying to upsell me on things I didn’t need. She walked me through my options, answered all my questions, and helped me achieve gorgeous, natural looking results. You can tell she truly cares about her clients and the work she does. I highly recommend!

– Elyssa Gehring, Google Review

I wouldn’t trust anyone else for my Botox!

Abby is phenomenal! Her expertise and attention to detail are exceptional, and she creates such a welcoming, comfortable experience from start to finish. She’s worked on me, my mom, and my Tía, and we’ve all walked out looking stunning. Even just a few days after my injections in notice a BEAUTIFUL difference and it just keeps getting better and better. These ladies are the best of the best, and I wouldn’t trust anyone else for my Botox! HIGHLY recommend!

– Alexis Moran-Moffatt, Google Review