A cluttered desk often leads to a cluttered mind, and the same applies to your entire office. If you run a business in the Mile High City, you understand that a clean workspace directly influences productivity and boosts team morale.
Finding a reliable cleaning crew, however, often feels like searching for a needle in a haystack. You need a team that shows up on time, cleans thoroughly, and respects your equipment.
I have investigated the local market to identify the best office cleaning in Denver, ensuring you find teams that deliver on their promises so you can focus on work instead of dusting.
How much does Office Cleaning cost in Denver?
Budgeting for a cleaning service doesn’t have to be a guessing game. Generally, you should expect to pay somewhere between $0.08 and $0.30 per square foot for standard maintenance.
If you prefer hourly rates, most decent crews charge about $40 to $55 per cleaner per hour. To put that in real terms, a small startup office might spend around $200 to $400 a month for basic upkeep.
On the other hand, sprawling corporate spaces that need daily attention or specialized sanitation could easily look at bills exceeding $2,000 every month.
1. Denver Office Cleaning Services Inc.

Website: https://www.denverofficecleaningservice.net/
Areas Served: Denver and nearby areas
Contact: +1 720-748-6678
Schedule:
- Sun – Fri: 10 AM – 9 PM
- Sat: 12 PM – 9 PM
Big brand reliability meets the hands-on care of a local owner with Denver Office Cleaning Services.
What stood out to me immediately is their independence, as they don’t franchise, and the owner is often directly involved in quality control.
They bring over a decade of experience and have geared their operations toward being entirely eco-friendly, which is a significant advantage if your office prioritizes sustainability.
I also appreciate that they don’t use subcontractors. This can mean you know who is walking through your doors for clean-ups.
When I spoke to their team about a potential project, I was genuinely impressed by how they handled the “custom scope” conversation, tailoring every detail rather than pushing a generic package.
Notably, they manage diverse environments, from medical centers to tech offices, ensuring high-touch points are sanitized correctly.
The only downside is for those looking for a single provider for both home and office, as they focus strictly on commercial and industrial sectors.
The team is extremely friendly, trustworthy, and reliable
The service is unbeatable. The team is extremely friendly, trustworthy, and reliable. The work is very consistent, our office always looks so nice when they are done. Keith is so helpful and accommodating. I tried 2 other local cleaning companies, before going with Denver Office Cleaning Services, definitely the best choice overall!
– Jennifer Pollard, Google Review
They always work with you professionally
Denver Office Cleaning services has been doing an outstanding job servicing our account. The greatest thing about this company is they offer quarterly carpet cleaning at no charge along with their regular cleaning service. They always work with you professionally and keep our office looking nice and clean.
– Brenda Volantin, Google Review
2. JAN-PRO Cleaning & Disinfecting in Colorado

Website: https://jan-pro.com/denver/
Address: 1720 S Bellaire St #600
Contact: +1 720-740-4720
Schedule: Mon – Fri: 8 AM – 5 PM
JAN-PRO is a heavyweight in the cleaning world for a reason.
Their proprietary “EnviroShield” system distinguishes them from competitors, using advanced technology to disinfect hard-to-reach areas that standard mops miss.
Medical and dental offices rely on this for non-negotiable hygiene. They also back their work with a guarantee: if a problem is identified and cannot be fixed within one business day, the next cleaning is free.
More importantly, their staff undergo rigorous certification to ensure every technician is highly trained and qualified. They arrive uniformed and fully insured, which offers real peace of mind knowing professionals are in your building.
However, while they are massive, they do have geographic limits. They list specific cities like Denver, Boulder, and Loveland, so if your office is in a more remote part of Colorado, you might be out of their range.
I’ve had a great experience with Jan-Pro!
I’ve had a great experience with Jan-Pro! Their customer service is outstanding-responsive, professional, and genuinely helpful! It is clear they care about their clients and take pride in what they do! I HIGHLY recommend!
– Brittany Mule, Google Review
Very pleased with this company
Very pleased with this company. They are very professional. We’ve been with them for a while now and they always take care of their customers in a timely manner. Highly recommend them.
– Catherine Bravo, Google Review
3. Denver Cleaning Service Company

Website: https://denvercleaningservicecompany.com/
Address: 1325 S Colorado Blvd Bldg B, Ste 501
Contact: +1 720-273-2762
Schedule: Mon – Fri: 8 AM – 5 PM
Denver Cleaning Service Company positions itself as an “on-site” partner rather than just a vendor.
Being family-owned gives them a level of care you don’t always find with national chains. They also offer deep steam carpet cleaning, going beyond basic vacuuming to truly wash carpets, which is a lifesaver during snowy Denver winters.
Their philosophy revolves around follow-through, often checking in after the job is done to ensure you are happy.
I particularly liked the convenience of getting a quote for their services through their quote forms. I tested this once to verify their efficiency, and I received a cost estimate in my inbox within minutes.
They also offer a 100% satisfaction guarantee, where their cleaning crew returns within 48 hours to fix issues if you have complaints with their team’s cleaning.
The main drawback to consider is their schedule. They operate Monday through Friday and are closed on weekends, which might require planning if you need deep cleaning done on a Saturday.
It was well worth the cost for us
We had never used this company for a cleaning before and they did a phenomenal job! It was well worth the cost for us.There was a slight hiccup where the cleaners accidentally tarnished our toaster oven, but it was entirely by accident and the Denver Cleaning Service company made it 100% right for us. We will definitely use them again in the future!
– Kenna Seawell, Google Review
The cleaning crew did an amazing job!
The cleaning crew did an amazing job! They arrived on time and were extremely professional. The entire process was seamless—from getting a quote to scheduling the service. I really appreciate the flexibility to book cleanings as needed, as well as the option to set up a monthly recurring service. Highly recommend this company!
– christina winborn, Google Review
4. Colorado Home And Office Cleaning LLC

Website: https://www.cohomeandofficeclean.com/
Address: 9601 E Iliff Ave
Contact: +1 720-731-4649
Schedule: Available 24 Hours
Businesses running at odd hours benefit most from this option.
Unlike many competitors that stick to a 9-to-5 window, these folks offer 24/7 availability. That means you can have them come in at 3 AM or late evening without disrupting your workflow.
Notably, they exclusively use non-toxic, eco-friendly products, so you won’t smell bleach the next morning, just clean air. These solutions keep the space safe for everyone, including office pets.
They’re also known for their “grid pattern” vacuuming technique, and while this sounds technical, it basically ensures every inch of your floor is covered.
On top of this, they have been around for over 10 years and are locally owned, so they understand the specific needs of Denver businesses.
They are also very transparent about not upselling you on things you don’t need.
The limitation is similar to others, as they focus strictly on the Denver metro area and about 13 surrounding cities, so if you’re a bit far out, you’ll have to miss out on the advantages they can offer.
I have used Colorado Home and Office Cleaning twice now
I have used Colorado Home and Office Cleaning twice now, both for move outs in apartments. Daylon is nothing but professional and does an exceptional job in an efficient timeframe. He is very responsive and always makes sure to check in on what you might want to focus on that day. He even helped me take a bunch of trash to my dumpster, which he certainly didn’t need to do, but was so appreciated. I will be returning as a customer any time I need an apartment cleaning!
– Carly Hollinshead, Google Review
I highly recommend this crew for their outstanding service
I have been consistently impressed with the exceptional service provided by Colorado Home And Office Cleaning over the past year. The team consistently maintains a high standard of cleanliness in our office, ensuring a welcoming and professional environment for our staff and visitors. Their attention to detail and reliability have made them a valuable partner in maintaining a pristine workplace. I highly recommend this crew for their outstanding service and dedication to excellence.
– Breezy Williams, Google Review
5. Big League Clean

Website: https://www.bigleagueclean.com/locations/denver/
Address: 1550 Larimer St
Contact: +1 720-896-7368
Schedule: Mon – Sun: 7 AM – 7 PM
Big League Clean focuses heavily on speed and communication. They respond to most inquiries in an average of 14 minutes. If you have ever waited days for a vendor to email you back, you know how valuable that speed is.
They assign a dedicated account manager who checks in bi-weekly, helping prevent small issues from turning into bigger problems.
When it comes to their services, they also handle standard janitorial work along with specialized services like window washing and water restoration.
Flexibility is another strong suit, with month-to-month agreements that work well for startups or businesses in transition. More importantly, their staff is fully vetted and insured, and they are NetVendor certified.
However, unlike some smaller “hybrid” cleaning companies in Denver that handle both residential and small boutique offices, Big League Clean is built for scale.
If you are a very small startup or a home-office user, you may find this month-to-month corporate agreement and large-scale operational style to be more industrial than what a small, intimate workspace requires.
I’ve had such a great experience with Big League Clean!
I’ve had such a great experience with Big League Clean! Their team is professional, thorough, and always reliable. Communication is excellent and they are super easy to work with. The quality of their cleaning is outstanding, and they consistently make sure everything looks perfect.
– Talya Abramov, Google Review
I would absolutely recommend Big League Clean!
I would absolutely recommend Big League Clean! They are true professionals and work diligently to provide top of the line service to their clients. The team is respectful with our work space, adaptable to possible changes/challenges that arise and communicates exceptionally well. Highly recommend!
– Nick Diaz, Google Review





